Dentinogenesis imperfecta (DI) is a genetic disorder affecting the developmental integrity of the dentin which results in weakened dentin. It is inherited as an autosomal dominant trait. The affected teeth, generally the posterior teeth will have to be extracted due to severity in wear and thereby possible fracture. This commonlyresults in loss of posterior occlusion and reduced vertical dimension. Apart from wear and fracture, anterior teeth may have an unesthetic appearance because of discoloration. Early diagnosis and treatment of DI is recommended, as it may prevent or intercept deterioration of the teeth and its occlusion. This article presents a case report of Prosthodontic Management of a patient diagnosed with Dentinogenesis Imperfecta.