Introduction: Non-specific low back pain is common cause of disability, with up to 90% of population experiencing pain at some stage in their lives. Psychosocial factors measure the psychological phenomena to the social environment and to pathophysiological changes within body. Psychosocial factors influence pain, disability, and response to treatment, Depression Anxiety Stress Scale (DASS-21) assessed the psychological and emotional states of the subject before and after the onset of pain. Methodology: 201 participants were selected for the study. Subjects were classified in 3 groups, group A – (young)- 16-35 years, group B (adults) - 36-55 years & group C (gediatrics) - 56-75 years. DASS-21 was assessed for levels of stress, anxiety & depression and PSEQ was evaluated for level of confidence to perform ADLs while in pain in different age groups. Result: Highest level of self-efficacy was seen in the participants of group B followed. The participants of group C showed low self-efficacy. VAS score was found to be lowest in the participants of group B. The participants of group B also exhibited lowest scores in all three domains of DASS-21 compared to group A and group B. Conclusion: The study concluded that measures across the groups A, B & C revealed presence of statistically significant difference in the scores of PSEQ, DASS-21 & VAS, among all three groups, group C showed lowest self-efficacy & lowest scores in all three domains of DASS-21 compared to group A and group B.