Asherman syndrome is the presence of adhesions in the endometrial cavity that can result in infertility or recurrent spontaneous abortion with or without amenorrhea. It can present with pain, menstrual abnormalities, recurrent pregnancy loss and infertility. These synechiae may be detected on a hysterogram or sonohysterogram, but are best shown with diagnostic hysteroscopy. Management includes hysteroscopic guided lysis of adhesions and attempt to restore uterine cavity anatomy. Platelet rich plasma, stem cells, growth factors, tissue engineering are being explored for endometrial regenerative therapy. Preventive measures need to be explored more. Efforts are needed in reducing adhesions post instrumentation especially in gravid uterus.