Advertisement!
Author Information Pack
Editorial Board
Hacekd by alahad
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
RFP Journal of Dermatology

Volume  10, Issue 1,  2025, Pages 17-20
 

Case Report

Role of Prolotherapy in Wound Bed Preparation in Grade 4 Ischial Pressure Injuries

Sriram V.S., Ravi Kumar Chittoria, Amrutha J.S. Role of Prolotherapy in Wound Bed Preparation in Grade 4 Ischial Pressure Injuries. RFP Jr of Drea 2025; 10(1): 17-20

Senior Resident, Department of Plastic Surgery, JIPMER, Pondicherry 605006, India.
2 Professor and Associate Dean (Academic), Head of IT Wing and Telemedicine, Department of Plastic Surgery and
Telemedicine, JIPMER, Pondicherry 605006, India.
3 MBBS, MS, Senior Resident, Department of Plastic Surgery, JIPMER, Pondicherry 605006, India.
 

Choose an option to locate / access this Article:
days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: 10.21088/jd.2582.3582 10125.3

Abstract

Background: Hypoalbuminemia is prevalent in patients undergoing major   abdominal surgeries and is associated with adverse postoperative outcomes, including prolonged hospital stays, higher infection rates, and increased mortality.   The clinical impact of albumin supplementation in these patients remains under scrutiny. Objective: This study evaluates whether al bumin supplementation   Background: Hypoalbuminemia is prevalent in patients undergoing major abdominal surgeries and is associated with adverse postoperative outcomes,  including prolonged hospital stays, higher infection rates, and increased mortality. The clinical impact of albumin supplementation in these patients remains under scrutiny. Objective: This study evaluates whether albumin supplementation in  hypoalbuminemicpatients(≤3.0g/dL)improvespostoperativeoutcomes. Methods: This retrospective study included patients who underwent major abdominal surgery between January 2021 and December 2024 at a tertiary care hospital. Patients with hypoalbuminemia were divided into two cohorts of 250 each: those who received postoperative albumin supplementation and those who did not. Outcomes measured included length of hospital stay (LOS), infection rates, ICU admission rates, and 30-day mortality. Results:    Background: Hypoalbuminemia is prevalent in patients undergoing major abdominal surgeries and is associated with adverse postoperative outcomes, including prolonged hospital stays, higher infection rates, and increased mortality. The clinical impact of albumin supplementation in these patients remains under scrutiny. Objective: This study evaluates whether albumin supplementation in  hypoalbuminemicpatients(≤3.0g/dL)improvespostoperativeoutcomes. Methods: This retrospective study included patients who underwent major abdominal surgery between January 2021 and December 2024 at a tertiary care hospital. Patients with hypoalbuminemia were divided into two cohorts of 250 each: those who received postoperative albumin supplementation and those who did not. Outcomes measured included length of hospital stay (LOS), infection rates, ICU admission rates, and 30-day mortality. Results: ThealbuminsupplementationgrouphadasignicantlyshorterLOS(8.1 vs. 11.4 days, p < 0.001) and lower infection rates (10% vs. 17%, p = 0.02). There   wasno     statisticallysignicantdifferenceinICUadmissionsor30-daymortality    between the two groups (p = 0.58 and p = 0.19, respectively). Multivariate regression identiedalbuminsupplementationasanindependentpredictorofreducedLOS and infection rates. Conclusion: Albumin supplementation in hypoalbuminemic patients post-major   abdominal surgery improves recovery metrics by reducing LOS and infection rates  healbuminsupplementationgrouphadasignicantlyshorterLOS(8.1 vs. 11.4 days, p < 0.001) and lower infection rates (10% vs. 17%, p = 0.02). There wasno   tatisticallysignicantdifferenceinICUadmissionsor30-daymortality between the two groups (p = 0.58 and p = 0.19, respectively). Multivariate regression    identiedalbuminsupplementationasanindependentpredictorofreducedLOS and infection rates.   Conclusion: Albumin supplementation in hypoalbuminemic patients post-major abdominal surgery improves recovery metrics by reducing LOS and infection Methods: This retrospective study included patients who underwent major abdominal surgery between January 2021 and December 2024 at a tertiary care hospital. Patients with hypoalbuminemia were divided into two cohorts of 250 each: those who received postoperative albumin supplementation and those who did not. Outcomes measure  d included length of hospital stay (LOS), infection rates, ICU admission rates, and 30-day mortality. Results:    ealbuminsupplementationgrouphadasignicantlyshorterLOS(8.1 vs. 11.4 days, p < 0.001) and lower infection rates (10% vs. 17%, p = 0.02). There wasno   statisticallysignicantdifferenceinICUadmissionsor30-daymortality between the two groups (p = 0.58 and p = 0.19, respectively). Multivariate regression identiedalbuminsupplementationasanindependentpredictorofreducedLOS and infection rates.  


Keywords : Hypoalbuminemia <3.5 g/dL • Length of hospital stay(LOS) • Post-operative albumin levels • Albumin supplementation
Corresponding Author : Ravi Kumar Chittoria