The success of green revolution not only backs on the uses of high yielding variety of crops but also on the pest control methods all over the world. A new epoch of pest control begins with the discovery of pesticide like DDT and Lindane in 1940, it takes almost three decades for us to realize the deleterious effect of these compound on flora and fauna on earth, but by that time a flush of new synthetic pesticide comes in use with very few long-term studies on their impact of nature. The main problem of use of pesticide is that a very few are there to be specific for a selected pest, and in consequences many other forms of life frequently fall victim of their action. Pesticide use not only affects the biodiversity of fields but severely change the nature of our aquatic life. Fish engage in recreation an imperative job in nutrient cycles because they store a large percentage of ecosystem nutrients in their tissues (Approx. 15-40%) (Kotillaetall 2012), transport nutrients farther than other aquatic animals and excrete nutrients in dissolved forms that are willingly available to chief producers. Although the influence of fish populations on food web structures, nutrient recycling, and productivity is well documented, little is known about the effects on the ecosystem of a reduction in the fish species richness. It is consequently of significant importance to evaluate the possible impacts of ongoing decreases in fish variety. Aquatic life is very sensitive to a wide variety of pesticide, chemical and toxic conditions may arise, not only from the spillage or deliberate discharge of  these chemicals into rivers and lakes, but also from many applications outside agriculture, such as silviculture (the growing and cultivation of trees), horticulture or public health, can also lead to a detrimental influence on fish populations. The current review will focus on the routes of contamination of pesticides in aquatic systems. Pesticides can create a great economic loss by fish deathrate on one hand and on the other hand add them unfit for human and animal consumption. These contaminated fish are very harmful for those who consume these infected fishes.