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A Prospective Study: On Clinical Profile and Outcome of Malaria in Pregnancy at Tertiary Care Centre in North-Western Maharashtra

Dilip R. Patil , Dilip R. Patil , Naresh S. Vidhate

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Indian Journal of Obstetrics and Gynecology 2(2):p 37-43, . | DOI:
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Abstract

Introduction: Malaria during pregnancy is a recognised risk factor for maternal and fetal complications and it is endemic in certain areas of our country. Pregnancy also enhances the severity of malaria particularly with P falciparum infestation. Malaria in pregnancy is a complex phenomenon and malaria epidemiology is rapidly changing, additional evidence is still required to understand how best to control malaria. Material and Methods: This is a prospective observational study conducted in the department of medicine of A.C.P.M. Medical College during the period from July 2009 to Feb 2014. Twenty seven pregnant women with sub types of malaria in pregnancy were studied. The maternal complications and outcome of pregnancy was studied. Observation: A total of 27 pregnant women patients with plasmodium falciparum, vivax and mixed malaria with age group 15 to 45 years (mean 26.29) There was statistically significant increase in the incidence of anemia(mean Hb 6.4gm%), thrombocytopenia(mean platelet count 65700/cmm), mean leucocyte count 9129 and mean random blood sugar 60.7mg/dl, high grade fever, headache, jaundice, altered sensorium observed in plasmodium falciparum infection during pregnancy. There was also increased 11.11% renal and hepatic failure, and 7.4% intrauterine fetal deaths in plasmodium falciparum malaria. Conclusion: Plasmodium falciparum malaria is more severe and life threatening in pregnant females as compared to plasmodium vivax, it was found in our study that either primigravida or multigravida. Plasmodium falciparum type of malaria causes more illness with higher incidence of complications, multiorgan involvement and supposedly bad prognosis.

Keywords: P.falciparum; P.vivax; Clinical profile; Anemia.


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  • Dilip R. Patil
    ,
  • Dilip R. Patil
    ,
  • Naresh S. Vidhate
    ,

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