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Histopathological Spectrum of Upper Gastrointestinal Tract Endoscopic Biopsies

Sanjay Gaiwale, , Tushar Kambale1 , Rumaanah Khan2 , Komal D Sawaimul3 , Sanjay Gaiwale4 , C R Gore5 , Banyameen Iqbal6

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Indian Journal of Forensic Medicine and Pathology 15(2):p 111-119, . | DOI: https://dx.doi.org/10.21088/ijfmp.0974.3383.15222.7
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Tushar Kambale, Sanjay Gaiwale, Rumaanah Khan, et al./ Histopathological Spectrum of Upper Gastrointestinal Tract Endoscopic Biopsies.Indian J Forensic Med Pathol.2022;15(2):111-119.

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Abstract

Introduction:  Upper GI diseases (lesions) are frequently seen in clinical practice. These are  associated with mortality and morbidity in patients with GI lesions. Early  diagnosis of inflammatory disorders, infectious diseases, physical, mechanical  and toxic reactions and neoplasms of upper gastrointestinal tract is possible  with endoscopic biopsies with its histopathological correlation.  Materials and methods: This prospective study was carried out on 162  patients in Dr. D.Y. Patil Medical college, Hospital and research centre, Pune  for a period of 2 years from June 2019-2021. Biopsy specimens were fixed in  10% formalin and routinely processed in Haematoxylin & Eosin stain. Results:  A total of 250 biopsy samples were obtained from 162 patients of which  188(75%) were from Stomach, 33 (13%) from Duodenum, 25(10%) from  Esophagus and 2% from gastro esophageal junction. Maximum biopsies were  carried out in the age group of 31-40 years. 149 (64.19%) of biopsies were  from males and 101 (35.8%) were from females. Among the total cases, 140  (86.41%) were non neoplastic lesions whereas 22 (13.58%) were neoplastic  lesions. Epigastric pain seen in 71 (43.8%) was the commonest symptom  ofupper gastrointestinal lesions.  Conclusion: The upper GI endoscopy helps in early detection of several  mucosal lesions, diagnosis of malignancies at early stages and of clinically  suspected lesions leading to prompt treatment.

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Authors and Affiliatione

  • Sanjay Gaiwale,
    ,
  • Tushar Kambale1
    ,
  • Rumaanah Khan2
    ,
  • Komal D Sawaimul3
    ,
  • Sanjay Gaiwale4
    ,
  • C R Gore5
    ,
  • Banyameen Iqbal6
    ,
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Cite this article

Tushar Kambale, Sanjay Gaiwale, Rumaanah Khan, et al./ Histopathological Spectrum of Upper Gastrointestinal Tract Endoscopic Biopsies.Indian J Forensic Med Pathol.2022;15(2):111-119.

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DOI: https://dx.doi.org/10.21088/ijfmp.0974.3383.15222.7
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