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Pattern of Congenital Anomalies: A Hospital Based Fetal Autopsy Study

Parameswari Babu. U., Assistant Professor, Department of pathology, Chittoor, Andhra Pradesh 517127, India. , Ranga Rao D.1 , Parameswari Babu U.2 , Kalyan K.3 , Muni Bhavani I.4

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Indian Journal of Forensic Medicine and Pathology 11(2):p 106-110, . | DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.11218.11
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Abstract

Congenital malformations are most common cause of perinatal death. Antenatal imaging studies can easily detect the problem, and can give an idea of diagnosis. However autopsy still plays a pivotal role in confirming the diagnosis and identifying actual cause of fetal loss.

Materials And Methods: This is a descriptive, cross-sectional study on 101 fetuses, over a period of 2 years from October 2014 to September 2016 referred to the Department of Pathology, Dr PSIMS & RF; which were an outcome of spontaneous abortions, intrauterine deaths, still births and of therapeutic abortions due to anomalies. This study is to determine overall incidence and distribution of various congenital anomalies and data was analyzed statistically.

Results: Total 101 consecutive perinatal autopsy were performed, 31 (30.6%) fetuses showing congenital anomalies with female (16.8%) predominance and M:F ratio 1:1.2. Common congenital anomalies were observed in this study included central nervous system defects - anencephaly and meningomyelocele being common. Other systemic anomalies are genitourinary system, gastrointestinal system, respiratory and musculoskeletol system were seen. Multiple syndromes such as Prune-belle, Meckel- gruber were observed in this study.

Keywords: Perinatal Autopsy; Congenital Anomalies.

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  • Parameswari Babu. U., Assistant Professor, Department of pathology, Chittoor, Andhra Pradesh 517127, India.
    ,
  • Ranga Rao D.1
    ,
  • Parameswari Babu U.2
    ,
  • Kalyan K.3
    ,
  • Muni Bhavani I.4
    ,
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DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.11218.11
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