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Case Report

Primitive Polar Spongioblastoma: A Rare Histopathological Entity

Shilpi Bhargava , Shilpi Bhargava , Kumud Gangwal , Shubha Gupta , Mansi Faujdar , Deepa Wadhwani

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Indian Journal of Pathology: Research and Practice 2(1):p 29-32, . | DOI:
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Abstract

Primitive Polar spongioblastoma is a very rare histopathological entity characterized by bipolar tumor cells with palisading nuclei showing immunoreactivity for neuron-specific enolase. The entity was first described by Russell and Cairns in 1947. It is classified as a high grade glioma with a very poor prognostic outcome. However, similar histological profile is often seen in many neuroepithelial tumors, and this category was earlier excluded from the World Health Organization (WHO) classification raising the question of its existence as a tumour entity. Presently, it is included in WHO classification in the category of CNS tumour of uncertain origin. To our knowledge, only a few cases of Primitive polar spongioblastoma have been reported so far. The present case of a 65 yr old male clinically presenting with vomiting & altered sensorium. MRI findings were inconclusive suggesting a mass lesion in the temporal lobe & a presumptive diagnosis of tumoral bleed was given.

Keywords: Glioma; Neuroepithelial; Palisading; Spongioblstoma. 

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  • Shilpi Bhargava
    ,
  • Shilpi Bhargava
    ,
  • Kumud Gangwal
    ,
  • Shubha Gupta
    ,
  • Mansi Faujdar
    ,
  • Deepa Wadhwani
    ,
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