Home > Journals > Indian Journal of Biology

Indian Journal of Biology

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Teratogenic and Embryotoxic Effects of Synthetic Pyrethroids on Chick (Gallus Domesticus) Embryo

Santi Ranjan Dey**** , Rita Chowdhury* , Soumima Chattoraj** , Ananya Bandyopadhyay*** , Santi Ranjan Dey****

Author Information
Licence:


Indian Journal of Biology 2(1):p 61-65, . | DOI: DOI: https://dx.doi.org/10.21088/ijb.2394.1391.2115.10
How Cite This Article:
Received : N/A         Accepted : N/A          Published : N/A
Abstract

The teratogenicity of commercial formulation of synthetic pyrethroids in chick embryo was evaluated. Fertilized eggs of Gallus domesticus were incubated for 6 days at 37° C. The eggs are divided into 8 batches, having 10 eggs in each batch. With the help of insulin syringe, 1 ml in each egg with following strength in each batch respectively, 0.0025mg/ml, 0.005 mg/ml, 0.0075 mg/ml, 0.01mg/ml, 0.0124mg/ml, 0.0175mg/ml, 0.025mg/ml of synthetic pyrethroid (Transflurithrin) was injected in the vegetal pole of the eggs. The synthetic pyrethroid was dissolved in normal saline. The dose was much less than the commercial formulation which is 8.8mg/ml, used as mosquito repellant. The control was injected with 1ml normal saline. After 14 days, recovered embryos were evaluated for mortality rate, wet body weight and gross morphological malfunction. The result revealed that embryonic mortality markedly increased with the quantity of pyrethroid. This experiment also shows 100%mortality of developing chick embryo in 0.025mg/ml dose. The significant decrease in wet body weight and significant increase in percentage of abnormal survivor was observed in dose dependent manner. Megalocephaly, exencephaly, sometimes twisted neck, low bone density were seen among survivor. The growth and development of digits also hampered. Reddish patch was seen all over the body of developing embryo. Parrot like beak, blunt beak was observed. An overview of external malfunction is seen by pyrethroid treated embryos. These finding suggests that synthetic pyerethroid exhibit embryotoxic and teratogenic effects in developing chick embryo. 

References

No records found.

Funding

Author Information

Authors and Affiliatione

  • Santi Ranjan Dey****
    ,
  • Rita Chowdhury*
    ,
  • Soumima Chattoraj**
    ,
  • Ananya Bandyopadhyay***
    ,
  • Santi Ranjan Dey****
    ,
Conflicts of Interest
Supplementary Information

Below is the link to the supplementary material.

Rights and Permissions


About this article

Cite this article

Licence:


Download citation

Received Accepted Published
N/A N/A N/A
DOI: DOI: https://dx.doi.org/10.21088/ijb.2394.1391.2115.10
Keywords

Article Level Metrics

Last Updated

Sunday 08 June 2025, 08:38:11 (IST)

23

Accesses

00
0
00

Citations


22
11
23

View full article metrics including social shares, article views and publishing history


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article


Reprint Order Form
Buy Single Article
Institutional Subscriptions

Share