Journal of Biochemistry and Biophysics
Full Text (PDF)
Licence:
Journal of Biochemistry and Biophysics 1(1):p 35-39, . | DOI:
Original Article
The Impact of Serum Uric Acid and Vitamin D on Essential Hypertension
Ramchandra K. Padalkar* , Ramchandra K. Padalkar* , Sangita M. Patil** , Sonali S. Bhagat** , Rahul A. Ghone** , Dhananjay V. Andure**
Author Information
Licence:
Journal of Biochemistry and Biophysics 1(1):p 35-39, . | DOI:
How Cite This Article:
Received : N/A
Accepted : N/A
Published : N/A
Abstract
Background: Hypertension is the third leading killer disease in the world and is responsible for 1 in every 8 deaths. Uric acid has been associated with hypertension in many studies involving different population but results were controversial and no information was found on the association between vitamin D insufficiency and elevated uric acid. The aim of present study was to assess the serum uric acid and vitamin D level in essential hypertension and try to find out its correlation. Material and Methods: The present study was case-control study. Total 90 subjects were included and divided into two groups. Group I consisted 45 subjects of essential hypertension in the age group 25-75 years while Group II consisted of age and sex matched 45 normal healthy individuals who served as control with no history of essential hypertension. Serum levels of uric acid, vitamin D were estimated in all the subjects under study. Values were expressed as mean± standard deviation. SYSTAT version 12 software was used for statistical analysis.Comparisons of study groups to control groups were done by applying student t test. Pearson’s correlation coefficient was used to find out the correlation between two variables. Results: Serum uric acid level was increased significantly (p<0.001) in essential hypertension as compared with controls. Correlation between uric acid and diastolic blood pressure and systolic blood pressure was positively correlated and significant. Correlation between Vitamin D and diastolic and systolic blood pressure was negatively correlated and non- ignificant. Conclusion: In the present study,It can be concluded that, the essential hypertension is associated with abnormalities in the level of serum uric acid and vitamin D. Serum uric acid and vitamin D can be used as biochemical markers to determine severity of hypertension and it may be beneficial for better management and for developing new treatment strategies.
Keywords: Essential Hypertension; Uric Acid; Vitamin D.
References (Bibliographical note)
No records found.
Funding Details
Author Information
Authors and Affiliatione
- Ramchandra K. Padalkar*
, - Ramchandra K. Padalkar*
, - Sangita M. Patil**
, - Sonali S. Bhagat**
, - Rahul A. Ghone**
, - Dhananjay V. Andure**
,
Rights & Permissions
Search for Similar Articles
You may search for similar articles that contain these
Article Level Metrics
Last UpdatedSaturday 19 April 2025, 05:33:40 (IST)
0
Accesses
00
0
00
Citations
22
11
23
View full article metrics including social shares, article views and publishing history
Article Keywords
Keyword Highlighting
Highlight selected keywords in the article text.
Timeline
| Received | N/A |
| Accepted | N/A |
| Published | N/A |