Journal of Biochemistry and Biophysics

Burns can severely damage a patient's physical and mental health. We should consider pain, hospital stays, lost workdays, and financial strain while handling these patients. Burn patients need rapid specialist care to reduce morbidity and death. Heparin is anti-inflammatory, allergic, histaminic, serotonin blocking, and proteolytic enzyme-blocking. Topical forms have been used to prevent burn extension, limit skin tissue loss, promote quicker healing with fewer contractures, relieve pain, reduce tissue oedema and weeping, prevent infection, and promote revascularization, granulation, and epithelialization of deeply burned tissue. We discuss topical heparin and burn care in this review.
 

After surviving from corona extra care of health is requisite in the society. The news of deaths during exercise in Gym were popular as many celebrities and famous personalities lost their lives. Many of them were corona survivors and post corona excessive exercises lead them to death. The present review study is analyzing the facts lying behind the cause of cardiovascular diseases CVDs. The CVDs increasing death rates in India at fast pace.

Background: Coronary heart disease is one of the leading cause of mortality in the world. D-dimer is direct marker of on going coagulation with fibrinolysis and high sensitive-C reactive protein not only marker of low grade chronic systemic inflammation but also directly involved in atherosclerosis.

Objectives: The aim of present was to investigate the diagnostic potential of the plasma D-Dimer and high sensitive-C reactive protein as inflammatory markers in Coronary heart disease.

Methods: In present case-control study 265 with various types coronary heart disease (age range 26 to 75) and 120 healthy age and sex matched volunteers formed the control group. Nyco Card reader was used for plasma D-Dimer estimation whereas high sensitive C-reactive protein was estimated by Latex turbidimetric method. Statistical software SYSTAT version-12 was used to analyze the data. Values were expressed as mean ± standard deviation and Comparisons of study groups and study groups to control groups were done by applying Z test. one way analysis of variance (ANOVA) test and tukey-Kramer multiple comparison test were used comparison.

Results: Plasma D-Dimer and high sensitive C-reactive protein levels were significantly higher (p<0.01) in patients with Coronary heart disease like Stable Angina, Unstable Angina and Myocardial Infacrction as compared to healthy controls.

Conclusion: D-Dimer seems to be independent cardiovascular risk factors, which might add relevant information. Circulating level of hs-CRP was significantly increased in patients with all types of Coronary heart disease but patients with Stable Angina had low level of high sensitive-C reactive protein as compared with patients with Unstable Angina and Myocardial infarction which shows that its role as acute inflammatory marker.