New Indian Journal of Surgery

 No Abstract

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Neo-adjuvant chemotherapy (NACT) is an integral part of multi-modality approach in the management of locally advanced breast cancer (LABC). It is required both for the local control (to ensure microscopically free margins during surgery) and distant or systemic control [1-6]. Development of resistance to chemotherapeutic agents is a major and evolving problem. Various markers like P-Glycoprotein, tumor suppressor gene p53, apoptotic markers( Bcl-2, Bax) have been studied to predict the response to NACT[1].

Key words: Hemoglobin, breast cancer, neoadjuvant, Chemotherapy.

This study was undertaken as peritonitis is one of the common surgical emergencies all over the world. However he mode of onset, etiological factors, morbidity and mortality will differ; depending upon available facilities for diagnosis, literacy status of the population, socio-economic status and religious notions., India is still developing country. The ignorance, illiteracy still persist all over the country which plays role in everyones life.The S.S.I.M.S & R.C, Davangere has got all kinds of cases of peritonitis presenting the sectional study of this country. All aspects of peritonitis have been considered in detail such as age and sex incidence, mode of onset, etiological factors, morbidity and mortality so as to fullfil all criteries of scientific study.

Key words: Peritonitis, Incidence 

Perforation of a Meckel’s diverticulum by a foreign body is a rare occurrence and can mimic. A 45 year old gentleman presented with signs and symptoms suggestive of acute appendicitis and a decision was taken to operate the patient. On exploration, the appendix was found to be normal and a fish bone was seen to be protruding through the Meckel’s diverticulum. The diverticulum was resected and end to end anastomosis was done. Patient had an uneventful recovery Pattern.

Urothelial neoplasms are a heterogeneous group of lesions, of which urothelial carcinoma is known for its divergent differentiation. Although majority of tumors are transitional cell carcinomas, the morphological spectrum of bladder cancer has expanded to include many new variants. The importance of recognition of these variants lies in the diagnostic, prognostic and therapeutic considerations that may occur as a result of a particular diagnosis. One such variant is micropapillary urothelial carcinoma [MPC]. Micropapillary carcinoma is an extremely rare but aggressive variant of urothelial carcinoma. The presence of this carcinoma should alert the urologists of its high grade and stage. We report a new case of bladder MPC in a 55 year old male and highlight the significance of recognizing this aggressive tumor.

Keywords: Micropapillary, urothelial carcinoma

Fibroadenoma is one of the most common benign breast disease seen in women in their late teens. Although ectopic benign breast tumour is more common along “Hughes line”, can also have an ectopic location., Whatever the position of ectopic breast tissue, it can undergo the same pathologic changes as seen in normally positioned breasts such as fibroadenoma and carcinoma., We report a case of fibroadenoma in unusual site, in 25year old female, who presented with painless swelling in the left infra-axillary region since 6months. It was diagnosed as fibroma or rare one fibroadenoma in axillary tail clinically., Fine needle aspiration cytology revealed benign fibro-epithelial lesion. The swelling was excised in toto and processed for histopathological examination. Histopathological examination confirmed fibroadenoma similar to the conventional type arising in the normal breast tissue.

Key words: Fibroadenoma, Unusual Site 

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